Luca Pinello, Ph.D.  Assistant Professor 

Luca is a Principal Investigator at Massachusetts General Hospital and Harvard Medical School. He received his BA,  MA and Phd in Computer Science and Mathematics from the University of Palermo in Italy. He had the good fortune to be part of the “omics” revolution and the opportunity to work on many computationally-challenging problems since he was an undergraduate student. During his postdoctoral research with Prof. Guo-Cheng Yuan at Dana-Farber Cancer Institute/Harvard School of Public health he studied the role of chromatin structure in gene regulation and developed computational methods for single cell analysis and epigenomics. He has a background in computer science and extensive experience in machine learning, data mining and web technologies. His research program uses computational approaches to systematically analyze the sources of variation that affect gene regulation: epigenetic variation, genetic variation and (single-cell) gene expression variability. In his free time he likes to hike, to cook and roast green coffee and to do photography.

Huidong_circleHuidong Chen,Ph.D. Research Fellow 

Huidong is a postdoctoral research fellow at Massachusetts General Hospital and Harvard Medical School. He completed both his undergraduate studies and Ph.D. in computer science at Tongji University in China. His research interests lie in the area of computational biology, ranging from machine learning methods to epigenome to transcriptome. In particular he is interested in developing computational methods for single cell analysis. Personally, he enjoys reading, hiking, running, and also a good Netflix binge.

kendellKendell Clement, Ph.D. Research Fellow

Kendell Clement joined the lab in July 2017 after completing his PhD in the Harvard-MIT Division of Health Sciences and Technology where he studied epigenetics in the contexts of pluripotency, embryonic development, and oncogenesis. He is interested in using computational algorithms to understand and interpret biological data, with particular interest in applications to genome modification and human disease.

jon_circle Jonathan Y. Hsu, Ph.D. student

Jonathan is a Ph.D. student in the MIT Biological Engineering department and received his BS in Bioengineering: Biotechnology from UCSD. He is currently co-advised by Professors Luca Pinello, Keith Joung, and Jim Collins and his research interests lie at the intersection of genome editing, epigenome engineering, and computational biology. Outside of research, he enjoys exploring the local Boston restaurant scene and exercising in order to keep in shape for the pipetting and coding he must do to graduate.

jon_circle Qiuming Yao, Ph.D. Research Fellow 

Qiuming Yao joined the lab in September 2017. He received his Ph.D. in Computer Science from University of Missouri, where he also obtained a separate M.A in Statistics. Before he joined lab, he performed a postdoctoral fellowship at Oak Ridge National Lab developing scalable computational tools for analyzing microbial ecosystems by integrating multiple ‘meta-omics’ data sets. His previous Ph.D. work focused on analysis and prediction of protein posttranslational modifications. He has broad interest in designing novel computational methods facilitating bulk or single cell ‘omics’ analyses in natural or engineered biological systems. Qiuming is co-mentored by Daniel Bauer, Ph.D.


Matthew Canver, MD,Ph.D., Visiting Research Fellow 

Samuele Cancellieri, Visiting student

Rick Farouni Ph.D., Research Fellow 

Giuseppe Ritrovato, Visiting student